Keep up to date with the latest news about IDEA, including the initiative's workshops, events and publications
Extended fragrance ingredients surveillance study (EFISS)—protocol for a clinical surveillance study on contact allergy to 7 fragrance materials in widespread use but hitherto not systematically patch tested
Study: An extended Reference Chemical Potency List (RCPL) for characterising the performance of New Approach Methodologies (NAMs) in measuring the skin sensitisation potency of fragrance chemicals
Skin sensitization potency prediction for 110 chemicals with three NAM approaches and comparison of the NAM-prediction to potency values for fragrance materials.
On 29 January 2026, the International Fragrance Association (IFRA) organised the 7th Review Meeting of the International Dialogue for the Evaluation of Allergens (IDEA) in Brussels.
‘Contact allergy (CA) is not uncommon in the population, including to various fragrance allergens. If not diagnosed correctly, allergic contact dermatitis (ACD) may ensue, because targeted allergen avoidance is not possible.
‘The development of a Reference Chemical Potency List (RCPL), and its purpose, has been described previously. That original RCPL comprised 33 chemicals, of varying skin sensitising activity, for each of which a discrete Potency Value (PV) was derived, based upon the best available human and/or animal (local lymph node assay) data.
IDEA organized a second workshop focusing on the capacity of NAMs to derive skin sensitization potency with the aim to derive a starting point (NESIL) for use in Quantitative Risk Assessment of fragrance ingredients.
IDEA organized a workshop reporting on the progress of developing an IDEA strategy to derive a starting point (NESIL) based on NAMs for use in the Quantitative risk Assessment, with the outcomes reported below.
Related to the IDEA sponsored Extended Fragrance Ingredients Surveillance Study (EFFIS)
Clinical surveillance study publication coming in early 2024
IDEA organized a workshop on the application of the RCPL in September 2023, with the outcomes reported below.
Brussels, 05 December 2022 – Stakeholders at the International Dialogue for the Evaluation of Allergens (IDEA) Annual Review meeting on 29 November 2022 reaffirmed their commitment to the project. Underway for nearly 10 years, IDEA seeks ways to improve consumer protection by bringing together various stakeholders including the fragrance industry, the dermatological community, and policy makers to build a new framework to assess fragrance allergens.