IDEA workshop on New Approach Methodologies (NAMs) – Derivation of a NESIL

IDEA organized a workshop reporting on the progress of developing an IDEA strategy to derive a starting point (NESIL) based on NAMs for use in the Quantitative risk Assessment, with the outcomes reported below.

In its effort on working towards a Quantitative Risk Assessment framework for skin sensitizers without animal data, IDEA organized a workshop on the status of the work done to date. This workshop welcomed a range of participants, including developers of NAMs, as well as representatives from industry, the Research Institute for Fragrance Materials (RIFM), the Joint Research Centre JRC )and the German BfR (Bundesinstitiut für Risikobewertung) as well as observers from DG Grow and the SCCS. It built on previous outcomes and agreed actions from the WSs held before. 

All documents from this meeting are available below:

1. Agenda
2. Welcome and Purpose of the WS
3. Purpose, Objectives and Challenges of the IDEA NAMs Project and development of the RCPL
4. The RIFM in vitro test program with quantitative endpoints
5. In vitro data and prediction approaches: initial results comparing the RCPL with data from the GARD-DR and Linear Regression models
6. Extending the RCPL
7. Outlook: How to tailor considerations of uncertainty into risk assessment
8. Key Conclusions
9. Final Workshop Report